Nucleo–cytoplasmic transport defects and protein aggregates in neurodegeneration

Abstract In the ongoing process of uncovering molecular abnormalities in neurodegenerative diseases characterized by toxic protein aggregates, nucleo-cytoplasmic transport defects have an emerging role. Several pieces of evidence suggest a link between neuronal protein inclusions and nuclear pore co...

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Bibliographic Details
Main Authors: Giacomo Bitetto, Alessio Di Fonzo
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Translational Neurodegeneration
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40035-020-00205-2