Spleen-dependent immune protection elicited by CpG adjuvanted reticulocyte-derived exosomes from malaria infection is associated with T cells population changes.

Spleen-dependent immune protection elicited by CpG adjuvanted reticulocyte-derived exosomes from malaria infection is associated with T cells population changes.

Reticulocyte-derived exosomes (rex) are 30-100 nm membrane vesicles of endocytic origin released during the maturation of reticulocytes to erythrocytes upon fusion of multivesicular bodies with the plasma membrane. Combination of CpG-ODN with rex obtained from BALB/c mice infected with the reticuloc...

Full description

Bibliographic Details
Main Authors: Lorena Martin-Jaular, Armando de Menezes-Neto, Marta Monguió-Tortajada, Aleix Elizalde-Torrent, Miriam Diaz-Varela, Carmen Fernandez-Becerra, Francesc E. Borras, Maria Montoya, Hernando A Del Portillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Malaria
Spleen
Vaccine
effector memory T cells
reticulocyte-derived exosomes
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00131/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00131/full

Similar Items