Overproduction of Sch9 leads to its aggregation and cell elongation in Saccharomyces cerevisiae.

The Sch9 kinase of Saccharomyces cerevisiae is one of the major TOR pathway effectors and regulates diverse processes in the cell. Sch9 belongs to the AGC kinase family. In human, amplification of AGC kinase genes is connected with cancer. However, not much is known about the effects of Sch9 overpro...

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Bibliographic Details
Main Authors: Polina Drozdova, Polina Lipaeva, Tatyana Rogoza, Galina Zhouravleva, Stanislav Bondarev
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5832320?pdf=render