The antimicrobial activity of gramicidin A is associated with hydroxyl radical formation.

Gramicidin A is an antimicrobial peptide that destroys gram-positive bacteria. The bactericidal mechanism of antimicrobial peptides has been linked to membrane permeation and metabolism disruption as well as interruption of DNA and protein functions. However, the exact bacterial killing mechanism of...

Full description

Bibliographic Details
Main Authors: Je-Wen Liou, Yu-Jiun Hung, Chin-Hao Yang, Yi-Cheng Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0117065