A Functional Polymorphism in B and T Lymphocyte Attenuator Is Associated with Susceptibility to Rheumatoid Arthritis

A Functional Polymorphism in B and T Lymphocyte Attenuator Is Associated with Susceptibility to Rheumatoid Arthritis

Inhibitory coreceptors are thought to play important roles in maintaining immunological homeostasis, and a defect in the negative signals from inhibitory coreceptors may lead to the development of autoimmune diseases. We have recently identified B and T lymphocyte attenuator (BTLA), a new inhibitor...

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Bibliographic Details
Main Authors: Mie Oki, Norihiko Watanabe, Takayoshi Owada, Yoshihiro Oya, Kei Ikeda, Yasushi Saito, Ryutaro Matsumura, Yohei Seto, Itsuo Iwamoto, Hiroshi Nakajima
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2011/305656

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http://dx.doi.org/10.1155/2011/305656

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