Batch correction of microarray data substantially improves the identification of genes differentially expressed in Rheumatoid Arthritis and Osteoarthritis

Batch correction of microarray data substantially improves the identification of genes differentially expressed in Rheumatoid Arthritis and Osteoarthritis

<p>Abstract</p> <p>Background</p> <p>Batch effects due to sample preparation or array variation (type, charge, and/or platform) may influence the results of microarray experiments and thus mask and/or confound true biological differences. Of the published approaches for...

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Bibliographic Details
Main Authors: Kupfer Peter, Guthke Reinhard, Pohlers Dirk, Huber Rene, Koczan Dirk, Kinne Raimund W
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Medical Genomics
Subjects:
Microarray analysis
Batch correction
Rheumatoid arthritis
Osteoarthritis
Collagen
Extracellular matrix
Online Access:http://www.biomedcentral.com/1755-8794/5/23

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http://www.biomedcentral.com/1755-8794/5/23

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