Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE2 pathway

Rheumatoid arthritis synovial fibroblasts promote TREM-1 expression in monocytes via COX-2/PGE2 pathway

Abstract Background Triggering receptor expressed on myeloid cells-1 (TREM-1) is inducible on monocyte/macrophages and neutrophils and amplifies the inflammatory response. The aim of this study was to determine whether rheumatoid arthritis synovial fibroblasts (RASF) promote the expression of TREM-1...

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Bibliographic Details
Main Authors: Anping Peng, Xinyi Lu, Jun Huang, Min He, Jianhua Xu, Hui Huang, Qubo Chen
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Arthritis Research & Therapy
Subjects:
Triggering receptor expressed on myeloid cells-1(TREM-1)
Monocytes
Rheumatoid arthritis synovial fibroblasts (RASF)
Prostaglandin E2 (PGE2)
Online Access:http://link.springer.com/article/10.1186/s13075-019-1954-3

Internet

http://link.springer.com/article/10.1186/s13075-019-1954-3

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