Independent Lineages of Highly Sulfadoxine-Resistant Plasmodium falciparum Haplotypes, Eastern Africa

Independent Lineages of Highly Sulfadoxine-Resistant Plasmodium falciparum Haplotypes, Eastern Africa

Sulfadoxine-resistant Plasmodium falciparum undermines malaria prevention with sulfadoxine/pyrimethamine. Parasites with a highly resistant mutant dihydropteroate synthase (dhps) haplotype have recently emerged in eastern Africa; they negated preventive benefits of sulfadoxine/pyrimethamine, and mig...

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Bibliographic Details
Main Authors: Steve M. Taylor, Alejandro L. Antonia, Whitney E. Harrington, Morgan M. Goheen, Victor Mwapasa, Ebbie Chaluluka, Michal Fried, Edward Kabyemela, Mwayi Madanitsa, Carole Khairallah, Linda Kalilani-Phiri, Antoinette K. Tshefu, Stephen J. Rogerson, Feiko O. ter Kuile, Patrick E. Duffy, Steven R. Meshnick
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2014-07-01
Series:Emerging Infectious Diseases
Subjects:
malaria
Plasmodium falciparum
parasites
sulfadoxine
drug resistance
lineages
Online Access:https://wwwnc.cdc.gov/eid/article/20/7/13-1720_article

Internet

https://wwwnc.cdc.gov/eid/article/20/7/13-1720_article

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