Structural modification of plasma HDL by phospholipids promotes efficient ABCA1-mediated cholesterol release

Structural modification of plasma HDL by phospholipids promotes efficient ABCA1-mediated cholesterol release

It has been suggested that ABCA1 interacts preferentially with lipid-poor apolipoprotein A-I (apoA-I). Here, we show that treatment of plasma with dimyristoyl phosphatidylcholine (DMPC) multilamellar vesicles generates preβ1-apoA-I-containing lipoproteins (LpA-I)-like particles similar to those of n...

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Bibliographic Details
Main Authors: Houssein Hajj Hassan, Sacha Blain, Betsie Boucher, Maxime Denis, Larbi Krimbou, Jacques Genest
Format: Article
Language:English
Published: Elsevier 2005-07-01
Series:Journal of Lipid Research
Subjects:
lipid-poor apolipoprotein A-I
ATP binding cassette transporter A1
cholesterol efflux
high density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520329977

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http://www.sciencedirect.com/science/article/pii/S0022227520329977

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