Therapeutic potential of PRL-3 targeting and clinical significance of <it>PRL-3 </it>genomic amplification in gastric cancer

Therapeutic potential of PRL-3 targeting and clinical significance of <it>PRL-3 </it>genomic amplification in gastric cancer

<p>Abstract</p> <p>Background</p> <p>Phosphatase of regenerating liver-3 (PRL-3) has deserved attention as a crucial molecule in the multiple steps of metastasis. In the present study, we examined the mechanisms regulating PRL-3 expression, and assessed the clinical pot...

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Bibliographic Details
Main Authors: Nishimiya Hiroshi, Kawamata Hiroshi, Waraya Mina, Katada Natsuya, Sakuramoto Shinichi, Kikuchi Shiro, Yamashita Keishi, Ooki Akira, Nakamura Kazunori, Watanabe Masahiko
Format: Article
Language:English
Published: BMC 2011-04-01
Series:BMC Cancer
Subjects:
PRL-3
gastric cancer
genomic amplification
targeted therapy
lymph node
Online Access:http://www.biomedcentral.com/1471-2407/11/122

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http://www.biomedcentral.com/1471-2407/11/122

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