Association of the PGC-1α rs8192678 Variant with Microalbuminuria in Subjects with Type 2 Diabetes Mellitus

PPAR-γ co-activator-1α (PGC-1α) is a tissue-specific transcriptional co-activator involved in the regulation of antioxidant enzymes. The A-allele of the rs8192678 PGC-1 α} (G>A) gene variant has previously been associated with nephropathy in Korean and Indian-Asian type 2 diabetes mellitus (T2DM)...

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Bibliographic Details
Main Authors: Sarah L. Prior, Amy R. Clark, Danielle A. Jones, Steve C. Bain, Steve J. Hurel, Steve E. Humphries, Jeffrey W. Stephens
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2012-0894