Molecular mechanism of parallel fiber-Purkinje cell synapse formation

Molecular mechanism of parallel fiber-Purkinje cell synapse formation

The cerebellum receives two excitatory afferents, the climbing fiber (CF) and the mossy fiber-parallel fiber (PF) pathway, both converging onto Purkinje cells (PCs) that are the sole neurons sending outputs from the cerebellar cortex. Glutamate receptor δ2 (GluRδ2) is expressed selectively in cerebe...

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Bibliographic Details
Main Authors: Masayoshi eMishina, Takeshi eUemura, Misato eYasumura, Tomoyuki eYoshida
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Neural Circuits
Subjects:
Purkinje cell
synapse formation
motor learning
neurexin
parallel fiber
glutamate receptor δ2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00090/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00090/full

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