Extracellular AMP Suppresses Endotoxemia-Induced Inflammation by Alleviating Neutrophil Activation

Extracellular AMP Suppresses Endotoxemia-Induced Inflammation by Alleviating Neutrophil Activation

Intracellular adenosine monophosphate (AMP) is indispensable for cellular metabolic processes, and it is interconverted to ADP and/or ATP or activates AMP-activated protein kinase (AMPK). However, the specific biological function of extracellular AMP has not been identified. We evaluated the effect...

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Bibliographic Details
Main Authors: Ye Hua, Dadong Liu, Danyi Zhang, Xu Wang, Qing Wei, Weiting Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
AMP
A1R
p38 MAPK
neutrophils
endotoxemia
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01220/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01220/full

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