Hypoxia-dependent drivers of melanoma progression

Abstract Hypoxia, a condition of low oxygen availability, is a hallmark of tumour microenvironment and promotes cancer progression and resistance to therapy. Many studies reported the essential role of hypoxia in regulating invasiveness, angiogenesis, vasculogenic mimicry and response to therapy in...

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Bibliographic Details
Main Authors: Simona D’Aguanno, Fabiana Mallone, Marco Marenco, Donatella Del Bufalo, Antonietta Moramarco
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-021-01926-6