Salidroside Attenuates Ventilation Induced Lung Injury via SIRT1-Dependent Inhibition of NLRP3 Inflammasome

Salidroside Attenuates Ventilation Induced Lung Injury via SIRT1-Dependent Inhibition of NLRP3 Inflammasome

Background: Salidroside (SDS) is the main effective ingredient of Rhodiola rosea L with a variety of pharmacologic properties. We aim to investigate the effects of SDS on ventilation induced lung injury (VILI) and explore the possible underlying molecular mechanism. Methods: Lung injury was induced...

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Bibliographic Details
Main Authors: Yan Wang, Chu-Fan Xu, Yu-Jian Liu, Yan-Fei Mao, Zhou Lv, Si-Yuan Li, Xiao-Yan Zhu, Lai Jiang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Salidroside
Ventilation-induced lung injury
NLRP3 inflammasome
SIRT1
Cyclic stretch
Online Access:http://www.karger.com/Article/FullText/477112

Internet

http://www.karger.com/Article/FullText/477112

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