Correlation of Parasite Burden, kDNA Integration, Autoreactive Antibodies, and Cytokine Pattern in the Pathophysiology of Chagas Disease

Correlation of Parasite Burden, kDNA Integration, Autoreactive Antibodies, and Cytokine Pattern in the Pathophysiology of Chagas Disease

Chagas disease (CD), caused by the protozoan Trypanosoma cruzi (T. cruzi), is the main parasitic disease in the Western Hemisphere. Unfortunately, its physiopathology is not completely understood, and cardiomegaly development is hard to predict. Trying to explain tissue lesion and the fact that only...

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Bibliographic Details
Main Authors: Moisés Wesley, Aline Moraes, Ana de Cássia Rosa, Juliana Lott Carvalho, Tatiana Shiroma, Tamires Vital, Nayra Dias, Bruna de Carvalho, Doralina do Amaral Rabello, Tatiana Karla dos Santos Borges, Bruno Dallago, Nadjar Nitz, Luciana Hagström, Mariana Hecht
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
Chagas disease
pathophysiology
correlation analysis
parasite burden
autoimmunity
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01856/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01856/full

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