Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus.

Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus.

We are extending the Cre/loxP site-specific recombination system to pigs, focussing on conditional and tissue-specific expression of oncogenic mutations to model human cancers. Identifying the location, pattern and extent of Cre recombination in vivo is an important aspect of this technology. Here w...

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Bibliographic Details
Main Authors: Shun Li, Tatiana Flisikowska, Mayuko Kurome, Valeri Zakhartchenko, Barbara Kessler, Dieter Saur, Alexander Kind, Eckhard Wolf, Krzysztof Flisikowski, Angelika Schnieke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4099177?pdf=render

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http://europepmc.org/articles/PMC4099177?pdf=render

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