N-Butanol Fraction of Wenxia Formula Extract Inhibits the Growth and Invasion of Non-Small Cell Lung Cancer by Down-Regulating Sp1-Mediated MMP2 Expression

N-Butanol Fraction of Wenxia Formula Extract Inhibits the Growth and Invasion of Non-Small Cell Lung Cancer by Down-Regulating Sp1-Mediated MMP2 Expression

Lung cancer is the most commonly diagnosed cancer and the leading cause of cancer death. It is necessary to develop effective anti-lung cancer therapeutics. Wenxia Formula (WXF), an empirical traditional Chinese herbal formula, has been reported to have significant antitumor activity. In this study,...

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Bibliographic Details
Main Authors: QianYu Bi, MengRan Wang, Fang Zhao, Meng Wang, XiangJun Yin, JiaZhao Ruan, DeLong Wang, XuMing Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Pharmacology
Subjects:
N-butanol fraction of wenxia formula extract
wenxia formula
non-small cell lung cancer
Sp1
MMP2
MMP9
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.594744/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.594744/full

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