Comparisons of Non-Gaussian Statistical Models in DNA Methylation Analysis
As a key regulatory mechanism of gene expression, DNA methylation patterns are widely altered in many complex genetic diseases, including cancer. DNA methylation is naturally quantified by bounded support data; therefore, it is non-Gaussian distributed. In order to capture such properties, we introd...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-06-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/15/6/10835 |