Comparisons of Non-Gaussian Statistical Models in DNA Methylation Analysis

As a key regulatory mechanism of gene expression, DNA methylation patterns are widely altered in many complex genetic diseases, including cancer. DNA methylation is naturally quantified by bounded support data; therefore, it is non-Gaussian distributed. In order to capture such properties, we introd...

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Bibliographic Details
Main Authors: Zhanyu Ma, Andrew E. Teschendorff, Hong Yu, Jalil Taghia, Jun Guo
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/15/6/10835