Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugs

Pleiotropic alterations in gene expression in Latin American Fasciola hepatica isolates with different susceptibility to drugs

Abstract Background Fasciola hepatica is the main agent of fasciolosis, a zoonotic disease affecting livestock worldwide, and an emerging food-borne disease in humans. Even when effective treatments are available, drugs are costly and can result in tolerance, liver damage and normally they do not pr...

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Bibliographic Details
Main Authors: Santiago Radio, Santiago Fontenla, Victoria Solana, Anna C. Matos Salim, Flávio Marcos Gomes Araújo, Pedro Ortiz, Cristian Hoban, Estefan Miranda, Valeria Gayo, Fabiano Sviatopolk-Mirsky Pais, Hugo Solana, Guilherme Oliveira, Pablo Smircich, José F. Tort
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Parasites & Vectors
Subjects:
Fascola hepatica
Drug resistance
American isolates
Triclabendazole
Albendazole
Transcriptomics
Online Access:http://link.springer.com/article/10.1186/s13071-017-2553-2

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http://link.springer.com/article/10.1186/s13071-017-2553-2

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