SALL4 promotes gastric cancer progression via hexokinase II mediated glycolysis

Abstract Background The stem cell factor SALL4 is reactivated in human cancers. SALL4 plays diverse roles in tumor growth, metastasis, and drug resistance, but its role in tumor metabolism has not been well characterized. Methods The glycolytic levels of gastric cancer cells were detected by glucose...

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Bibliographic Details
Main Authors: Meng Shao, Jiayin Zhang, Jiahui Zhang, Hui Shi, Yu Zhang, Runbi Ji, Fei Mao, Hui Qian, Wenrong Xu, Xu Zhang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Cancer Cell International
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12935-020-01275-y