Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis

Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis

Objectives: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries. Protein tyrosine phosphatase 1B (PTP1B), a negative modulator of insulin and cytokine signaling, is a therapeutic target for type 2 diabetes and obesity. We investigated the impact of...

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Main Authors: Águeda González-Rodríguez, M. Pilar Valdecantos, Patricia Rada, Annalisa Addante, Inés Barahona, Esther Rey, Virginia Pardo, Laura Ruiz, Laura M. Laiglesia, María J. Moreno-Aliaga, Carmelo García-Monzón, Aránzazu Sánchez, Ángela M. Valverde
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817306853

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http://www.sciencedirect.com/science/article/pii/S2212877817306853

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