The study of the apoptogenic effect of pyrimidine derivatives on murine leukemia cells

BACKGROUND: In the light of the recent findings concerning the role of apoptosis and of tumor cell enzymes in cancer chemotherapy, the interest in pyrimidine derivatives has greatly increased. Thio- and hydrazine- pyrimidines were synthesized as potential antimetabolites inhibiting the biosynthesis...

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Bibliographic Details
Main Authors: Gorneva Galina, Mateva Rada, Gugova Roumyana, Golovinsky Evgeny
Format: Article
Language:English
Published: Institute of Oncology, Sremska Kamenica, Serbia 2005-01-01
Series:Archive of Oncology
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-7310/2005/0354-73100502062G.pdf