Phenotypic and Functional Alterations in Circulating Memory CD8 T Cells with Time after Primary Infection.

Memory CD8 T cells confer increased protection to immune hosts upon secondary viral, bacterial, and parasitic infections. The level of protection provided depends on the numbers, quality (functional ability), and location of memory CD8 T cells present at the time of infection. While primary memory C...

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Bibliographic Details
Main Authors: Matthew D Martin, Marie T Kim, Qiang Shan, Ramakrishna Sompallae, Hai-Hui Xue, John T Harty, Vladimir P Badovinac
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4618693?pdf=render