Sanhuang Xiexin Tang Ameliorates Type 2 Diabetic Rats via Modulation of the Metabolic Profiles and NF-κB/PI-3K/Akt Signaling Pathways

Sanhuang Xiexin Tang Ameliorates Type 2 Diabetic Rats via Modulation of the Metabolic Profiles and NF-κB/PI-3K/Akt Signaling Pathways

Sanhuang Xiexin Tang (SXT), a classic prescription, has been clinically used to cure diabetes for thousands of years, but its mechanism remains unclear. Here, a systematic in-depth research was performed to unravel how it worked by the signaling pathway and metabonomics analysis. Our studies were co...

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Bibliographic Details
Main Authors: Xiaoyan Wei, Jinhua Tao, Yumeng Shen, Suwei Xiao, Shu Jiang, Erxin Shang, Zhenhua Zhu, Dawei Qian, Jinao Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Pharmacology
Subjects:
T2DM
Sanhuang Xiexin Tang
NF-κB
PI-3K/AKT
metabonomics
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00955/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.00955/full

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