A higher risk of acute rejection of human kidney allografts can be predicted from the level of CD45RC expressed by the recipients' CD8 T cells.

A higher risk of acute rejection of human kidney allografts can be predicted from the level of CD45RC expressed by the recipients' CD8 T cells.

Although transplantation is the common treatment for end-stage renal failure, allograft rejection and marked morbidity from the use of immunosuppressive drugs remain important limitations. A major challenge in the field is to identify easy, reliable and noninvasive biomarkers allowing the prediction...

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Bibliographic Details
Main Authors: Laurence Ordonez, Isabelle Bernard, Marianne Chabod, Jean-François Augusto, Valerie Lauwers-Cances, Christelle Cristini, Maria-Cristina Cuturi, Jean-François Subra, Abdelhadi Saoudi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3722168?pdf=render

Internet

http://europepmc.org/articles/PMC3722168?pdf=render

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