The Molecular Landscape of Hürthle Cell Thyroid Cancer Is Associated with Altered Mitochondrial Function—A Comprehensive Review

The Molecular Landscape of Hürthle Cell Thyroid Cancer Is Associated with Altered Mitochondrial Function—A Comprehensive Review

Hürthle cell thyroid carcinoma (HTC) accounts for 3–5% of all thyroid malignancies. Widely invasive HTC is characterized by poor prognosis and limited responsiveness to standard therapy with radioiodine. The molecular landscape of HTC is significantly different from the genetic signature seen in oth...

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Bibliographic Details
Main Authors: Sonam Kumari, Ruth Adewale, Joanna Klubo-Gwiezdzinska
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
mitochondria
metabolism
Hürthle cell
oxidative phosphorylation
thyroid cancer
oncogenes
Online Access:https://www.mdpi.com/2073-4409/9/7/1570

Internet

https://www.mdpi.com/2073-4409/9/7/1570

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