LXR/RXR ligand activation enhances basolateral efflux of β-sitosterol in CaCo-2 cells

LXR/RXR ligand activation enhances basolateral efflux of β-sitosterol in CaCo-2 cells

To examine whether intestinal ABCA1 was responsible for the differences observed between cholesterol and β-sitosterol absorption, ABCA1-facilitated β-sitosterol efflux was investigated in CaCo-2 cells following liver X receptor/retinoid X receptor (LXR/RXR) activation. Both the LXR agonist T0901317...

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Bibliographic Details
Main Authors: F. Jeffrey Field, Ella Born, Satya N. Mathur
Format: Article
Language:English
Published: Elsevier 2004-05-01
Series:Journal of Lipid Research
Subjects:
adenosine 5′-triphosphate binding cassette transporter A1
absorption
cholesterol
intestine
fatty acid
liver X receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318319

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http://www.sciencedirect.com/science/article/pii/S0022227520318319

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