The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation.

The G Protein-Coupled Receptor RAI3 Is an Independent Prognostic Factor for Pancreatic Cancer Survival and Regulates Proliferation via STAT3 Phosphorylation.

Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest tumors worldwide. Understanding the function of gene expression alterations is a prerequisite for developing new strategies in diagnostic and therapy. GPRC5A (RAI3), coding for a seven transmembrane G protein-coupled receptor is known t...

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Bibliographic Details
Main Authors: Elisabeth Jahny, Hai Yang, Bin Liu, Beatrix Jahnke, Franziska Lademann, Thomas Knösel, Petra Rümmele, Robert Grützmann, Daniela E Aust, Christian Pilarsky, Axel Denz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5256936?pdf=render

Internet

http://europepmc.org/articles/PMC5256936?pdf=render

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