Tarantula toxins use common surfaces for interacting with Kv and ASIC ion channels

Tarantula toxins that bind to voltage-sensing domains of voltage-activated ion channels are thought to partition into the membrane and bind to the channel within the bilayer. While no structures of a voltage-sensor toxin bound to a channel have been solved, a structural homolog, psalmotoxin (PcTx1),...

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Bibliographic Details
Main Authors: Kanchan Gupta, Maryam Zamanian, Chanhyung Bae, Mirela Milescu, Dmitriy Krepkiy, Drew C Tilley, Jon T Sack, Vladimir Yarov-Yarovoy, Jae Il Kim, Kenton J Swartz
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06774