Preparation and in vitro characterization of retinoic acid-loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) micelles

Preparation and in vitro characterization of retinoic acid-loaded poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) micelles

In order to achieve the controlled release of all-trans-retinoic acid (ATRA), poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) (PCL-PEG-PCL) copolymer with average molecular weight of 5.34 kDa was synthesized. The nanosized micelles were prepared from copolymer by nano-precipitation m...

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Bibliographic Details
Main Authors: Ebrahim Shakiba, Saeedeh Khazaei, Marziyeh Hajialyani, Bandar Astinchap, Ali Fattahi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone); micelle; all trans retinoic acid (atra); h1299; cytotoxicity
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2017;volume=12;issue=6;spage=465;epage=478;aulast=Shakiba

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2017;volume=12;issue=6;spage=465;epage=478;aulast=Shakiba

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