Reduced T regulatory cell response during acute Plasmodium falciparum infection in Malian children co-infected with Schistosoma haematobium.

Regulatory T cells (Tregs) suppress host immune responses and participate in immune homeostasis. In co-infection, secondary parasite infections may disrupt the immunologic responses induced by a pre-existing parasitic infection. We previously demonstrated that schistosomiasis-positive (SP) Malian ch...

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Bibliographic Details
Main Authors: Kirsten E Lyke, Abdoulaye Dabo, Charles Arama, Modibo Daou, Issa Diarra, Amy Wang, Christopher V Plowe, Ogobara K Doumbo, Marcelo B Sztein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3279404?pdf=render