Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication.
Coronaviruses are of veterinary and medical importance and include highly pathogenic zoonotic viruses, such as SARS-CoV and MERS-CoV. They are known to efficiently evade early innate immune responses, manifesting in almost negligible expression of type-I interferons (IFN-I). This evasion strategy su...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-02-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC5310923?pdf=render |