Indoleamine 2,3-Dioxygenase 2 Immunohistochemical Expression in Resected Human Non-small Cell Lung Cancer: A Potential New Prognostic Tool

Indoleamine 2,3-dioxygenase 2 (IDO2) is an analog of the tryptophan degrading and immunomodulating enzyme indoleamine 2,3-dioxygenase 1 (IDO1). Although the role of IDO1 is largely understood, the function of IDO2 is not yet well-elucidated. IDO2 overexpression was documented in some human tumors, b...

Full description

Bibliographic Details
Main Authors: Martina Mandarano, Guido Bellezza, Maria Laura Belladonna, Jacopo Vannucci, Alessio Gili, Ivana Ferri, Chiara Lupi, Vienna Ludovini, Giulia Falabella, Giulio Metro, Giada Mondanelli, Rita Chiari, Lucio Cagini, Fabrizio Stracci, Fausto Roila, Francesco Puma, Claudia Volpi, Angelo Sidoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00839/full