Bacillus thuringiensis Cry5B protein is highly efficacious as a single-dose therapy against an intestinal roundworm infection in mice.

Intestinal parasitic nematode diseases are one of the great diseases of our time. Intestinal roundworm parasites, including hookworms, whipworms, and Ascaris, infect well over 1 billion people and cause significant morbidity, especially in children and pregnant women. To date, there is only one drug...

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Bibliographic Details
Main Authors: Yan Hu, Sophia B Georghiou, Alan J Kelleher, Raffi V Aroian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2830470?pdf=render