S100A8 and S100A9 Promote Apoptosis of Chronic Eosinophilic Leukemia Cells

S100A8 and S100A9 Promote Apoptosis of Chronic Eosinophilic Leukemia Cells

S100A8 and S100A9 function as essential factors in inflammation and also exert antitumor or tumorigenic activity depending on the type of cancer. Chronic eosinophilic leukemia (CEL) is a rare hematological malignancy having elevated levels of eosinophils and characterized by the presence of the FIP1...

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Bibliographic Details
Main Authors: Ji-Sook Lee, Na Rae Lee, Ayesha Kashif, Seung-Ju Yang, A. Reum Nam, Ik-Chan Song, Soo-Jung Gong, Min Hwa Hong, Geunyeong Kim, Pu Reum Seok, Myung-Shin Lee, Kee-Hyung Sung, In Sik Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
S100 protein
chronic eosinophilic leukemia
TLR4
FIP1L1-PDGFRα
imatinib resistance
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01258/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.01258/full

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