Photoregulated fluxional fluorophores for live-cell super-resolution microscopy with no apparent photobleaching

Super-resolution microscopy with spontaneously blinking dyes is dependent on pH and polarity of the medium. Here the authors introduce a photoactivatable fluxional fluorophore for live cell imaging that allows control over the fraction of spontaneously blinking molecules independently of medium prop...

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Bibliographic Details
Main Authors: Elias A. Halabi, Dorothea Pinotsi, Pablo Rivera-Fuentes
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09217-7