Identification of candidate driver genes in common focal chromosomal aberrations of microsatellite stable colorectal cancer.

Identification of candidate driver genes in common focal chromosomal aberrations of microsatellite stable colorectal cancer.

Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. Chromosomal instability (CIN) is a major driving force of microsatellite stable (MSS) sporadic CRC. CIN tumours are characterised by a large number of somatic chromosomal copy number aberrations (SCNA) that frequently affect onco...

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Bibliographic Details
Main Authors: George J Burghel, Wei-Yu Lin, Helen Whitehouse, Ian Brock, David Hammond, Jonathan Bury, Yvonne Stephenson, Rina George, Angela Cox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3867468?pdf=render

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http://europepmc.org/articles/PMC3867468?pdf=render

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