Structural Insight into Anaphase Promoting Complex 3 Structure and Docking with a Natural Inhibitory Compound

Structural Insight into Anaphase Promoting Complex 3 Structure and Docking with a Natural Inhibitory Compound

Background: Anaphase promoting complex (APC) is the biggest Cullin-RING E3 ligase and is very important in cell cycle control; many anti-cancer agents target this. APC controls the onset of chromosome separation and mitotic exit through securin and cyclin B degradation, respectively. Its APC3 subun...

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Bibliographic Details
Main Authors: Hamzeh Rahimi, Mohammad Ali Shokrgozar, Armin Madadkar-Sobhani, Reza Mahdian, Alireza Foroumadi, Morteza Karimipoor
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Advanced Biomedical Research
Subjects:
Anaphase promoting complex
bioinformatics
tetratrico-peptide repeat domain
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2017;volume=6;issue=1;spage=26;epage=26;aulast=Rahimi

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http://www.advbiores.net/article.asp?issn=2277-9175;year=2017;volume=6;issue=1;spage=26;epage=26;aulast=Rahimi

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