EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

<p>Abstract</p> <p>Background</p> <p>Cancer stem cells are thought to be responsible for the initiation and progression of cancers. In non-small cell lung cancers (NSCLCs), Hoechst 33342 dye effluxing side population (SP) cells are shown to have stem cell like propertie...

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Bibliographic Details
Main Authors: Singh Sandeep, Trevino Jose, Bora-Singhal Namrata, Coppola Domenico, Haura Eric, Altiok Soner, Chellappan Srikumar P
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Molecular Cancer
Subjects:
Cancer stem-like cells
Side-population cells
Self-renewal
EGFR
Sox2
Online Access:http://www.molecular-cancer.com/content/11/1/73

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http://www.molecular-cancer.com/content/11/1/73

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