Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model

Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model

Novel interventions that do not rely on daily adherence to ART are needed to achieve sustained viral remission for perinatally infected children, who currently rely on lifelong ART. Considering the risks and expense associated with ART interruption trials, the identification of biomarkers of viral r...

Full description

Bibliographic Details
Main Authors: Ria Goswami, Ashley N. Nelson, Joshua J. Tu, Maria Dennis, Liqi Feng, Amit Kumar, Jesse Mangold, Riley J. Mangan, Cameron Mattingly, Alan D. Curtis, Veronica Obregon-Perko, Maud Mavigner, Justin Pollara, George M. Shaw, Katharine J. Bar, Ann Chahroudi, Kristina De Paris, Cliburn Chan, Koen K. A. Van Rompay, Sallie R. Permar
Format: Article
Language:English
Published: American Society for Microbiology 2019-09-01
Series:mBio
Subjects:
analytical treatment interruption
hiv reservoir
pediatric hiv cure
shiv
Online Access:https://doi.org/10.1128/mBio.01971-19

Internet

https://doi.org/10.1128/mBio.01971-19

Similar Items