The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain

AMPA receptors are comprised of different combinations of GluR1-GluR4 (also known as GluA1-GluA4 and GluR-A to GluR-D) subunits. The GluR2 subunit is subject to Q/R site RNA editing by the ADAR2 enzyme, which converts a codon for glutamine (Q), present in the GluR2 gene, to a codon for arginine (R)...

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Bibliographic Details
Main Authors: Amanda Lorraine Wright, Bryce eVissel
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2012.00034/full