Methionine Diet Evoked Hyperhomocysteinemia Causes Hippocampal Alterations, Metabolomics Plasma Changes and Behavioral Pattern in Wild Type Rats

Methionine Diet Evoked Hyperhomocysteinemia Causes Hippocampal Alterations, Metabolomics Plasma Changes and Behavioral Pattern in Wild Type Rats

L-methionine, an essential amino acid, plays a critical role in cell physiology. High intake and/or dysregulation in methionine (Met) metabolism results in accumulation of its intermediate(s) or breakdown products in plasma, including homocysteine (Hcy). High level of Hcy in plasma, hyperhomocystein...

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Bibliographic Details
Main Authors: Maria Kovalska, Eva Baranovicova, Dagmar Kalenska, Anna Tomascova, Marian Adamkov, Libusa Kovalska, Jan Lehotsky
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
methionine diet
hyperhomocysteinemia
morris water maze
neurodegeneration
wild-type rats
Online Access:https://www.mdpi.com/1422-0067/22/9/4961

Internet

https://www.mdpi.com/1422-0067/22/9/4961

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