Angiotensin II contributes to renal fibrosis independently of Notch pathway activation.

Angiotensin II contributes to renal fibrosis independently of Notch pathway activation.

Recent studies have described that the Notch signaling pathway is activated in a wide range of renal diseases. Angiotensin II (AngII) plays a key role in the progression of kidney diseases. AngII contributes to renal fibrosis by upregulation of profibrotic factors, induction of epithelial mesenchyma...

Full description

Bibliographic Details
Main Authors: Carolina Lavoz, Raquel Rodrigues-Diez, Alberto Benito-Martin, Sandra Rayego-Mateos, Raúl R Rodrigues-Diez, Matilde Alique, Alberto Ortiz, Sergio Mezzano, Jesús Egido, Marta Ruiz-Ortega
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3392235?pdf=render

Internet

http://europepmc.org/articles/PMC3392235?pdf=render

Similar Items