HER2-/HER3-Targeting Antibody—Drug Conjugates for Treating Lung and Colorectal Cancers Resistant to EGFR Inhibitors

Epidermal growth factor receptor (EGFR) is one of the anticancer drug targets for certain malignancies, including nonsmall cell lung cancer (NSCLC), colorectal cancer (CRC), and head and neck squamous cell carcinoma. However, the grave issue of drug resistance through diverse mechanisms persists, in...

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Bibliographic Details
Main Author: Kimio Yonesaka
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
ADC
Online Access:https://www.mdpi.com/2072-6694/13/5/1047