Characterization of <it>gana-1</it>, a Caenorhabditis elegans gene encoding a single ortholog of vertebrate α-galactosidase and α-N-acetylgalactosaminidase

Characterization of <it>gana-1</it>, a Caenorhabditis elegans gene encoding a single ortholog of vertebrate α-galactosidase and α-N-acetylgalactosaminidase

<p>Abstract</p> <p>Background</p> <p>Human α-galactosidase A (α-GAL) and α-N-acetylgalactosaminidase (α-NAGA) are presumed to share a common ancestor. Deficiencies of these enzymes cause two well-characterized human lysosomal storage disorders (LSD) – Fabry (α-GAL defic...

Full description

Bibliographic Details
Main Authors: Kostrouchová Marta, Ledvinová Jana, Poupětová Helena, Dobrovolný Robert, Sikora Jakub, Hujová Jana, Hřebíček Martin
Format: Article
Language:English
Published: BMC 2005-01-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/6/5

Internet

http://www.biomedcentral.com/1471-2121/6/5

Similar Items