Characterization of <it>gana-1</it>, a Caenorhabditis elegans gene encoding a single ortholog of vertebrate α-galactosidase and α-N-acetylgalactosaminidase
<p>Abstract</p> <p>Background</p> <p>Human α-galactosidase A (α-GAL) and α-N-acetylgalactosaminidase (α-NAGA) are presumed to share a common ancestor. Deficiencies of these enzymes cause two well-characterized human lysosomal storage disorders (LSD) – Fabry (α-GAL defic...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2005-01-01
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Series: | BMC Cell Biology |
Online Access: | http://www.biomedcentral.com/1471-2121/6/5 |