The role of extracelluar matrix in osteosarcoma progression and metastasis

The role of extracelluar matrix in osteosarcoma progression and metastasis

Abstract Osteosarcoma (OS) is the most common primary bone malignancy and responsible for considerable morbidity and mortality due to its high rates of pulmonary metastasis. Although neoadjuvant chemotherapy has improved 5-year survival rates for patients with localized OS from 20% to over 65%, outc...

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Bibliographic Details
Main Authors: Juncheng Cui, Dylan Dean, Francis J. Hornicek, Zhiwei Chen, Zhenfeng Duan
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Extracellular matrix
Osteosarcoma
Metastasis
Prognostic biomarker
Therapeutic target
Online Access:http://link.springer.com/article/10.1186/s13046-020-01685-w

Internet

http://link.springer.com/article/10.1186/s13046-020-01685-w

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