Inosine Released from Dying or Dead Cells Stimulates Cell Proliferation via Adenosine Receptors

Inosine Released from Dying or Dead Cells Stimulates Cell Proliferation via Adenosine Receptors

IntroductionMany antitumor therapies induce apoptotic cell death in order to cause tumor regression. Paradoxically, apoptotic cells are also known to promote wound healing, cell proliferation, and tumor cell repopulation in multicellular organisms. We aimed to characterize the nature of the regenera...

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Bibliographic Details
Main Authors: Yi Zhao, Jin Chen, Ricardo A. Chaurio, Christian Maueröder, Anja Derer, Manfred Rauh, Andriy Kost, Yi Liu, Xianming Mo, Axel Hueber, Rostyslav Bilyy, Martin Herrmann, Luis E. Muñoz
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Immunology
Subjects:
melanoma
adenosine receptor
inosine
proliferation
repopulation
apoptosis
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00504/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00504/full

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