Protective immunity and safety of a genetically modified influenza virus vaccine.

Protective immunity and safety of a genetically modified influenza virus vaccine.

Recombinant influenza viruses are promising viral platforms to be used as antigen delivery vectors. To this aim, one of the most promising approaches consists of generating recombinant viruses harboring partially truncated neuraminidase (NA) segments. To date, all studies have pointed to safety and...

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Main Authors: Rafael Polidoro Alves Barbosa, Ana Paula Carneiro Salgado, Cristiana Couto Garcia, Bruno Galvão Filho, Ana Paula de Faria Gonçalves, Braulio Henrique Freire Lima, Gabriel Augusto Oliveira Lopes, Milene Alvarenga Rachid, Andiara Cristina Cardoso Peixoto, Danilo Bretas de Oliveira, Marco Antônio Ataíde, Carla Aparecida Zirke, Tatiane Marques Cotrim, Érica Azevedo Costa, Gabriel Magno de Freitas Almeida, Remo Castro Russo, Ricardo Tostes Gazzinelli, Alexandre de Magalhães Vieira Machado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4057169?pdf=render

Internet

http://europepmc.org/articles/PMC4057169?pdf=render

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