Superoxide dismutase in amyotrophic lateral sclerosis patients homozygous for the D90A mutation

The most common of the amyotrophic lateral sclerosis (ALS)-associated superoxide dismutase-1 (SOD1) mutations, D90A, differs from others in its high structural stability and by the existence of both recessive and dominant inheritance. Here SOD1 in CNS and peripheral organs from five ALS patients hom...

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Bibliographic Details
Main Authors: P. Andreas Jonsson, Karin S. Graffmo, Peter M. Andersen, Stefan L. Marklund, Thomas Brännström
Format: Article
Language:English
Published: Elsevier 2009-12-01
Series:Neurobiology of Disease
Subjects:
ALS
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109002253